What are biostimulators made from?
Biostimulators are made from a variety of substances, including synthetic and natural materials such as poly-L-lactic acid (PLLA), calcium hydroxyapatite (CaHA), polycaprolactone (PCL), and hyaluronic acid hybrids. These materials encourage the body to produce collagen and elastin, which are essential for maintaining skin elasticity and firmness.
You can find out a little more about each type of biostimulator below:
Poly-L-lactic acid (PLLA)
PLLA is a synthetic, biodegradable polymer that, when injected, can gradually stimulate collagen production over several months, leading to a fuller, more youthful appearance.
The brands to know: Sculptra.
Sculptra is a Poly-L-lactic acid-based injectable dermal filler, designed to provide a gradual and natural-looking improvement in skin texture and facial volume
The brands to know: JULÄINE™
JULÄINE™ is getting very favourable reviews from practitioners who are using it for nasolabial folds (aka smile lines) and marionette lines. That’s because its PLLA microspheres have a highly uniform particle size and degrade slowly, which makes them very helpful for restoring volume in depressed skin.
Calcium hydroxyapatite (CaHA)
Calcium hydroxyapatite (CaHA) is a naturally occurring mineral found in human bones and teeth. In aesthetics, it is used as a dermal filler in the form of tiny, smooth particles suspended in a gel. CaHA provides immediate volume and stimulates collagen production for longer-lasting results.
The brands to know: Radiesse.
Radiesse is a dermal filler that contains calcium hydroxyapatite (CaHA) microspheres. It is used to correct moderate to severe facial wrinkles and folds and for hand rejuvenation. Radiesse provides immediate volume and lifts while also stimulating the body’s natural collagen production for extended results.
The brands to know: HArmonyCa.
HArmonyCa is an innovative hybrid injectable that combines calcium hydroxyapatite (CaHA) with hyaluronic acid (HA). This dual-action treatment provides the immediate volumising and hydrating effects of HA while stimulating collagen production through CaHA for longer-lasting improvements in skin quality.
Polycaprolactone (PCL)
Polycaprolactone (PCL) is a biodegradable polymer. As a biostimulator, PCL-based fillers stimulate collagen production and provide long-lasting volume and skin rejuvenation.
The brand to know: Ellanse.
Ellanse is a brand of dermal fillers made from polycaprolactone (PCL) microspheres. It offers immediate volume correction and stimulates the production of collagen, with results that can last from one to four years depending on the specific product used.