Philosophers now seem to agree that frequentism is an untenable strategy to explain the meaning of probabilities. Nevertheless, I want to revive frequentism, and I will do so by grounding probabilities on typicality in the same way as the thermodynamic arrow of time can be grounded on typicality within statistical mechanics. This account, which I will call typicality frequentism, will evade the major criticisms raised against previous forms of frequentism. In this theory, probabilities arise within a (...) physical theory from statistical behavior of almost all initial conditions. The main advantage of typicality frequentism is that it shows which kinds of probabilities (that also have empirical relevance) can be derived from physics. Although one cannot recover all probability talk in this account, this is rather a virtue than a vice, because it shows which types of probabilities can in fact arise from physics and which types need to be explained in different ways, thereby opening the path for a pluralistic account of probabilities. (shrink)

I show that frequentism, as an explanation of probability in classical statistical mechanics, can be extended in a natural way to a decoherent quantum history space, the analogue of a classical phase space. The result is a form of finite frequentism, in which Gibbs’ concept of an infinite ensemble of gases is replaced by the quantum state expressed as a superposition of a finite number of decohering microstates. It is a form of finite and actual frequentism (as (...) opposed to hypothetical frequentism) insofar as all the microstates exist, in keeping with the decoherence-based Everett interpretation, and some versions of pilot-wave theory. (shrink)

In a multi-source study, we examine how frequent change interacts with ethical leadership to reduce turnover intentions. We argue that ethical leaders enhance employees’ state self-esteem, which explains the moderating effect of ethical leadership. Results from 124 employee-coworker-supervisor triads revealed that ethical leadership moderated the relationship between frequent change and turnover intention such that the relationship was positive only when ethical leadership was low. The moderating relationship could be shown to be mediated by employees’ state self-esteem.

Barbour’s interpretation of Mach’s principle led him to postulate that gravity should be formulated as a dynamical theory of spatial conformal geometry, or in his terminology, “shapes.” Recently, it was shown that the dynamics of General Relativity can indeed be formulated as the dynamics of shapes. This new Shape Dynamics theory, unlike earlier proposals by Barbour and his collaborators, implements local spatial conformal invariance as a gauge symmetry that replaces refoliation invariance in General Relativity. It is the purpose of this (...) paper to answer frequent questions about (new) Shape Dynamics, such as its relation to Poincaré invariance, General Relativity, Constant Mean (extrinsic) Curvature gauge, earlier Shape Dynamics, and finally the conformal approach to the initial value problem of General Relativity. Some of these relations can be clarified by considering a simple model: free electrodynamics and its dual shift symmetric formulation. This model also serves as an example where symmetry trading is used for usual gauge theories. (shrink)

Frequent observation: sexualities, self‐surveillance, confession and the construction of the active patient Following Foucault’s analyses of the development of the disciplinary power of the medical gaze, this paper describes the themes that are relocating the ‘active patient’ as the central object of health scrutiny by professionals. A key element in these discourses has been the deployment of power through disciplinary knowledge and techniques of social control through ritual forms of confession, thereby positing the patient/client as the subject of self‐surveillance. The (...) individual is also engaged their own sexuality, performativity and ‘truths’ of sexual experience. These Foucauldian insights have constructed the notion of surveillance medicine, whereby with the assistance of professional technologies, not only the patient’s body but also the ‘self’ can be probed through incitement to confess. However, the actor is not docile; resistances to disciplinary techniques are evident and within the professional practices of the clinic, there is resistance to the power of the erotic. The paper draws on recent research on the social construction of male sexualities in the fields of genitourinary practice, and explores how the ceremonial practices of the clinic engage with the rise of surveillance medicine and the medicalisation of everyday life. The individual actor is exhorted to engage in increased sexual and medical self‐surveillance and to be recruited in the project of becoming an ‘active patient’. It concludes with an examination of some of the implications this surveillance of self may have for practitioners in terms of power and the professional lens through which the sexualised, symbolic body is viewed. (shrink)

Calls for public engagement on emerging agricultural technologies, including genetic engineering of farm animals, have resulted in the development of information that people can interact and engage with online, including “Frequently Asked Questions” (FAQs) developed by organizations seeking to inform or influence the debate. We conducted a frame analysis of FAQs webpages about genetic engineering of farm animals developed by different organizations to describe how questions and answers are presented. We categorized FAQs as having a regulatory frame (emphasizing or challenging (...) the adequacy of regulations), an efficiency frame (emphasizing precision and benefits), a risks and uncertainty frame (emphasizing unknown outcomes), an animal welfare frame (emphasizing benefits for animals) or an animal dignity frame (considering the inherent value of animals). Animals were often featured as the object of regulations in FAQs, and questions about animals were linked to animal welfare regulations. The public were represented using a variety of terms (public, consumer) and pronouns (I, we). Some FAQs described differences between technology terms (gene editing, genetic modification) and categorized technologies as either well-established or novel. This framing of the technology may not respond to actual public concerns on the topic. Organizations seeking to use FAQs as a public engagement tool might consider including multiple viewpoints and actual questions people have about genetic engineering. (shrink)

Frequently Asked Questions about Time This supplement provides background information about many of the topics discussed in both the main Time article and its companion article What Else Science Requires of Time. It is not intended that this article be read in order by section number. Table of Contents What Are Durations, Instants, Moments, and … Continue reading Frequently Asked Questions about Time →.

Some patients who have been diagnosed as “dead by neurologic criteria” continue to exhibit certain brain functions, most commonly, neuroendocrine functions. This preservation of neurologic function after the diagnosis of “brain death” or “brainstem death” is an ongoing source of controversy and concern in the medical, bioethics, and legal literatures. Most obviously, if some brain function persists, then it is not the case that all functions of the entire brain have ceased and hence, declaring such a patient to be “dead” (...) would be a false positive, in any nation with so-called “whole brain death” laws. Furthermore, and perhaps more concerning, the preservation of any brain function necessarily entails the preservation of some amount of brain perfusion, thereby raising the concern as to whether additional areas of neural tissue may remain viable, including areas in the brainstem. These and other considerations cast significant doubt on the reliability of diagnosing either “brain death” or “brainstem death.”. (shrink)

The commentators' responses to The Illusion of Conscious Will reveal a healthy range of opinions – pro, con, and occasionally stray. Common concerns and issues are summarized here in terms of 11 “frequently asked questions,” which often center on the theme of how the experience of conscious will supports the creation of the self as author of action.

Mintz (2003) found that in English child-directed speech, frequently occurring frames formed by linking the preceding (A) and succeeding (B) word (A_x_B) could accurately predict the syntactic category of the intervening word (x). This has been successfully extended to French (Chemla, Mintz, Bernal, & Christophe, 2009). In this paper, we show that, as for Dutch (Erkelens, 2009), frequent frames in German do not enable such accurate lexical categorization. This can be explained by the characteristics of German including a less restricted (...) word order compared to English or French and the frequent use of some forms as both determiner and pronoun in colloquial German. Finally, we explore the relationship between the accuracy of frames and their potential utility and find that even some of those frames showing high token-based accuracy are of limited value because they are in fact set phrases with little or no variability in the slot position. (shrink)

How come quantum theory has anything to do with mind? Is your theory refutable? What is the point of all the technical detail? Do you suggest that the operation of the brain involves large scale quantum coherence? Isn't large scale quantum coherence necessary to solve the problem of the unity of consciousness? How does a many-minds interpretation survive Occam's razor? What, briefly, is your current philosophical position? What is your understanding of the relationship between mind and brain for split-brain patients? (...) Do you believe that the mind can survive the death of the brain? No journal reference is given for several of the recent papers on your home page. Where will these papers be printed? How are the “source” and “pdf” versions of the papers on your home page produced and viewed? Why does the page with your photograph behave oddly in some browsers? Where can I find an elementary introduction to the interpretation of quantum theory? Doesn't decoherence theory solve all the problems of the interpretation of quantum theory? How do the ambiguities of decoherence affect the many-worlds interpretation? Could you expand on your answers to the two previous questions? Why isn't the conventional interpretation of quantum theory adequate? What about the Bohm interpretation? What about consistent histories? Does the present many-minds interpretation solve all the problems? (shrink)

CEO turnover is a critical event in an organization that influences organizational processes and performance. The objective of this study is to investigate whether workforce diversity might have a resilience effect on firm performance under the frequency of CEO turnover. Based on a sample of 409 Korean firms from 2010 to 2015, our results show that firms with more frequent CEO turnover have a lower firm performance. However, firms with more gender and education-level diversity could buffer the disruptive effect of (...) frequent CEO turnover on firm performance to offer a benefit to the organization. Our theory and findings suggest that effectively managing diverse workforce can be a resilience factor in an uncertain organizational environment because diverse workforce has complementary skills and behaviors that can cope better with uncertainty and signals social inclusion of an organization, thus fostering a long-term exchange relationship. These findings contribute to the literature on CEO turnover and diversity. (shrink)

The study consists of a systematic review, where the objective was set: to analyze the impact of the use of mobile devices in early childhood, answering the following questions: What is the frequency of the use of mobile devices in early childhood? What is the impact of frequent use of mobile devices in early childhood? Scientific productions from the SCOPUS, Web of Science, Gale OneFile Psychology and ProQuest databases were analyzed, publications made from 2020 to 2023. The study is based (...) on the PRISMA methodology, which consists of a flow diagram that allows selecting the studies for their construction ( Higgins and Green, 2011), which have allowed the methods and techniques of the studies to be systematized in an organized way. The reviewed productions provide empirical and theoretical data in the field of psychology and social sciences. The results reveal that 22.7% of 18-month-old children and 94.6% of 5-year-old children use the mobile device 60 minutes a day. High levels of mobile device use at the age of 5 years are associated with hyperactivity, difficulties with attention, concentration and behavioral problems. Frequent mobile device use at the age of 18 months can cause many attention difficulties because they are susceptible to external experiences and excessive media use that can hinder development in attention networks. (shrink)

The view that chances are relative frequencies of occurrence within actual, finite reference classes has long been written off. I argue that it ought to be reconsidered. Focusing on non-deterministic chance, I defend a version of finite frequentism in which reference classmates are required to have qualitatively identical pasts. While my analysis can evade or resist several standard objections, it has a counterintuitive consequence: non-trivial chances entail the existence of past light cones that are perfect intrinsic duplicates. In mitigation, (...) I argue that our scientific knowledge is consistent with the hypothesis that there are many such duplicates in the actual world. Moreover, my analysis has some striking advantages: it is simple, it is metaphysically undemanding, and it makes possible a satisfying explanation of the chance–credence connection. 1 Introduction2 Target3 Sketch and Skirmish4 Articulation5 Standard Worries5.1 Frequency tolerance5.2 Leibniz’s dictum5.3 Single case chance5.4 Missing values5.5 Explanation5.6 Counterfactual chances6 Chance and Credence6.1 An indefeasible indifference intuition6.2 Articulating the credence principle6.3 Appraising the credence principle7 Confirmation8 Laws9 Summing Up. (shrink)

This article examines how the formation of markets in bottled water has relied on assembling a particular subject: the subject of hydration. The discourse of hydration is a conspicuous feature of efforts to market bottled water, allowing companies to appeal to scientifically framed principles and ideas of health in order to position the product as an essential component in self-health and healthy lifestyles. Alongside related principles, such as the ‘8 × 8 rule’, hydration has done much to establish new practices (...) of water drinking and consumption in which the consumer appears to be always at risk of dehydration and must engage in practices of ‘frequent sipping’. This article traces the emergence of the concept of hydration from its origins in exercise science and explores its circulation, contemporary uses and purchase. I argue that the appeal to biomedical languages and concepts found in the discourse of hydration connects with much broader ways of conceiving and acting upon the self that have become prevalent in contemporary society – what Rose and Novas call ‘biological citizenship’ – indicating how the ensemble of hydration participates in wider-ranging transformations in forms of rule. The story of hydration reveals how biomedical techniques of the self can be made to double up as ‘market devices’ by offering specific procedures for assessing the self and calculating the body’s needs. In order to grasp these developments, I position the health sciences, and health and fitness in particular, as a potent site of popular culture in which bodies learn to be affected by the procedures of scientific experiment. A critical grasp of this context is best enabled, I argue, by situating the producers and consumers of scientific principles and commercial products as embodied and looking at their interconnection in processes of emergence. Through these means, we can begin to develop a fully materialized account of the question: how have we become so thirsty? (shrink)

Scientific misconduct obstructs the advance of knowledge in science. Its impact in some disciplines is still poorly known, as is the frequency in which it is detected. Here, I examine how frequently editors of ecology and evolution journals detect scientist misconduct. On average, editors managed 0.114 allegations of misconduct per year. Editors considered 6 of 14 allegations (42.9%) to be true, but only in 2 cases were the authors declared guilty, the remaining being dropped for lack of proof. The annual (...) rate of allegations that were probably warranted was 0.053, although the rate of demonstrated misconduct was 0.018, while the rate of false or erroneous allegations was 0.024. Considering that several cases of misconduct are probably not reported, these findings suggest that editors detect less than one-third of all fraudulent papers. (shrink)

In this study, we investigate the impact of frequent service learning on the emotional, personal development, and leadership characteristics of business students at a Catholic university in the United States. We examine the aforementioned impact of frequent service learning through a novel panel data set provided by the University’s Institute for Leadership and Service, ranging from the years 2008 through 2015. Specifically, we conduct an empirical analysis across the emotional, personal development, and leadership dimensions, and examine the too-much-of-a-good-thing effect of (...) Pierce and Aguinis in relation to service learning. Our results suggest that business students experience statistically significant increases in several emotional, personal development, and leadership dimensions as the number of service learning experiences increases. We provide mixed evidence of the TMGT effect when aggregating the emotion and personal development dimensions against the number of service-learning experiences via examination of cross-dimensional averages. Our study yields implications for the optimal number of service learning projects for business schools. (shrink)

This is the sequel to my “Fifteen Arguments Against Finite Frequentism” ( Erkenntnis 1997), the second half of a long paper that attacks the two main forms of frequentism about probability. Hypothetical frequentism asserts: The probability of an attribute A in a reference class B is p iff the limit of the relative frequency of A ’s among the B ’s would be p if there were an infinite sequence of B ’s. I offer fifteen arguments against (...) this analysis. I consider various frequentist responses, which I argue ultimately fail. I end with a positive proposal of my own, ‘hyper-hypothetical frequentism’, which I argue avoids several of the problems with hypothetical frequentism. It identifies probability with relative frequency in a hyperfinite sequence of trials. However, I argue that this account also fails, and that the prospects for frequentism are dim. (shrink)

This quantitative analysis of direct references to the two most frequently cited Greek, Roman, Christian, Islamic, and Jewish philosophers within Aquinas’ opus, with a detailed examination of Avicenna, addressed a gap in the systematic enumeration of sources using a three-tiered methodology, which included documentation of Aquinas’ direct citations from Leonina, cross-checked with Index Thomisticus, and statistically validated. The findings demonstrated dominance of Christian Augustinus and Dionysius and Greek Aristoteles and Plato, with the highest concentrations in Summa Theologiæ and Expositio Aristotelis, (...) respectively, while affirming Islamic philosophy’s secondary influence through Averroes and Avicenna. Roman and Jewish sources had the fewest references. A near-perfect correlation between the Leonina and Index Thomisticus datasets was established. This study’s data-driven approach to Thomistic philosophy bridged traditional textual scholarship with digital humanities and by documenting Aquinas’ direct sources, refined our understanding of the divergent philosophical traditions’ influences on Aquinas’ philosophical and theological synthesis. Its originality and contribution lie in establishing a consistent methodology for documenting direct references to multiple sources across a complete philosophical opus and facilitating replicable textual and computational analysis in Thomistic, medieval, and manuscript studies. (shrink)

Many supporters of ‘moral bioenhancement’ (MBE), the use of biomedical interventions for moral improvement, have been criticised for having unrealistic proposals. The interventions they suggest have often been called infeasible and their implementation plans vague or unethical. I dispute these criticisms by showing that various interventions to implement MBE are practically and ethically feasible enough to warrant serious consideration. Such interventions include transcranial direct current stimulation over the medial and dorsolateral prefrontal cortex, as well as supplementation with lithium and omega-3. (...) Considering their efficacy and feasibility, it is strange that these interventions have rarely been proposed or discussed as MBE. I review evidence that each of those interventions can reduce antisocial behaviour, reduce racial bias, increase executive function or increase prosocial traits like fairness and altruism. I then specify and defend realistic, ethically permissible ways to implement these interventions, especially for violent offenders and public servants—the former as rehabilitation and the latter to meet the high standards of their occupations. These interventions could be given to violent offenders in exchange for a reduced sentence or compulsorily in some cases. Potential intervention methods for non-prisoners include increasing the USDA-recommended dose of omega-3, encouraging food companies to supplement their products with omega-3 or trace lithium, requiring MBE for employment as a police officer or political leader, and insurance companies providing discounts for undergoing MBE. In some reasonably limited form, using these interventions may be a good first step to implement the project of MBE. (shrink)

The standard representation theorem for expected utility theory tells us that if a subject’s preferences conform to certain axioms, then she can be represented as maximising her expected utility given a particular set of credences and utilities—and, moreover, that having those credences and utilities is the only way that she could be maximising her expected utility. However, the kinds of agents these theorems seem apt to tell us anything about are highly idealised, being always probabilistically coherent with infinitely precise degrees (...) of belief and full knowledge of all a priori truths. Ordinary subjects do not look very rational when compared to the kinds of agents usually talked about in decision theory. In this paper, I will develop an expected utility representation theorem aimed at the representation of those who are neither probabilistically coherent, logically omniscient, nor expected utility maximisers across the board—that is, agents who are frequently irrational. The agents in question may be deductively fallible, have incoherent credences, limited representational capacities, and fail to maximise expected utility for all but a limited class of gambles. (shrink)

According to finite frequentism, the probability of an attribute A in a finite reference class B is the relative frequency of actual occurrences of A within B. I present fifteen arguments against this position.

Frequent itemset mining is the most important step of association rule mining. It plays a very important role in incremental data environments. The massive volume of data creates an imminent need to design incremental algorithms for the maximal frequent itemset mining in order to handle incremental data over time. In this study, we propose an incremental maximal frequent itemset mining algorithms that integrate subjective interestingness criterion during the process of mining. The proposed framework is designed to deal with incremental data, (...) which usually come at different times. It extends FP-Max algorithm, which is based on FP-Growth method by pushing interesting measures during maximal frequent itemset mining, and performs dynamic and early pruning to leave uninteresting frequent itemsets in order to avoid uninteresting rule generation. The framework was implemented and tested on public databases, and the results found are promising. (shrink)

Frequent pattern mining is an effective approach for spatiotemporal association analysis of mobile trajectory big data in data-driven intelligent transportation systems. While existing parallel algorithms have been successfully applied to frequent pattern mining of large-scale trajectory data, two major challenges are how to overcome the inherent defects of Hadoop to cope with taxi trajectory big data including massive small files and how to discover the implicitly spatiotemporal frequent patterns with MapReduce. To conquer these challenges, this paper presents a MapReduce-based Parallel (...) Frequent Pattern growth algorithm to analyze the spatiotemporal characteristics of taxi operating using large-scale taxi trajectories with massive small file processing strategies on a Hadoop platform. More specifically, we first implement three methods, that is, Hadoop Archives, CombineFileInputFormat, and Sequence Files, to overcome the existing defects of Hadoop and then propose two strategies based on their performance evaluations. Next, we incorporate SF into Frequent Pattern growth algorithm and then implement the optimized FP-growth algorithm on a MapReduce framework. Finally, we analyze the characteristics of taxi operating in both spatial and temporal dimensions by MR-PFP in parallel. The results demonstrate that MR-PFP is superior to existing Parallel FP-growth algorithm in efficiency and scalability. (shrink)

Frequent evolutionary birth and death events have created a large quantity of biologically important, lineage‐specific DNA within mammalian genomes. The birth and death of DNA sequences is so frequent that the total number of these insertions and deletions in the human population remains unknown, although there are differences between these groups, e.g. transposable elements contribute predominantly to sequence insertion. Functional turnover – where the activity of a locus is specific to one lineage, but the underlying DNA remains conserved – can (...) also drive birth and death. However, this does not appear to be a major driver of divergent transcriptional regulation. Both sequence and functional turnover have contributed to the birth and death of thousands of functional promoters in the human and mouse genomes. These findings reveal the pervasive nature of evolutionary birth and death and suggest that lineage‐specific regions may play an important but previously underappreciated role in human biology and disease. (shrink)

In this paper, I develop a novel interval-based approach to some well-known semantic puzzles related to aspect shift, in particular, to the interaction of for-adverbials with accomplishment and achievement verbs that take indefinite, bare plural, and mass noun complements. My approach is based on the insight that implicit frequentative aspect plays a central role in this interaction, a fact that was largely ignored in previous analyses. Specifically, I interpret frequentative aspect as an abstract verb-level pluractional operator that brings about aspect (...) shift and that is responsible for the distribution of subevent times and subevent participants over the event time of an atelic sentence. What Zucchi and White (2001) call "the aspectual effect of frequency adverbs" thus becomes the general rule for all frequentatively understood for-adverbial sentences. Linguistic support for silent verb-level frequentativity in English is drawn from overt frequentative aspect marking in West Greenlandic verbs. (shrink)

We give a short, critical review of the issue of decoherence. We estab- lish the most general framework in which decoherence can be discussed, how it can be quantified and how it can be measured. We focus on environment induced decoher- ence and its degree of usefulness for the interpretation of quantum theory. We finally discuss the emergence of a classical world. An overall emphasis is given in pointing at common fallacies and misconceptions.

Intelligent design is the science that studies how to detect intelligence. Recall astronomer Carl Sagan’s novel Contact about the search for extraterrestrial intelligence (or SETI). Sagan based the SETI researchers’ methods of design detection on scientific practice. Real-life SETI researchers have thus far failed to detect designed signals from distant space. But if they encountered such a signal, as the astronomers in Sagan’s novel did, they too would infer design. Intelligent design research currently focuses on developing reliable methods of design (...) detection and then applying these methods, especially to biological systems. (shrink)

The issue of recurrent attenders to eye casualties has received little discussion in the ethics and health policy literature. As many ophthalmology departments offer a walk-in emergency service, protocols need to be in place to ensure appropriate use of this resource and also to identify potential psychiatric comorbidity in such attenders. We illustrate the problem with a recent case.A 42-year-old woman self-presented 14 times over a 4-month period to the same ophthalmic accident and emergency unit. ….

In the following discussion, we address the ethical dilemma of who should benefit from the many frequent-flier programs used by airlines. The issue of central concern involves whether the employer or employee are acting unethically when either of them choose to be the beneficiary from frequent-flier programs. Once this issue is decided, we then determine if the benefits outweigh the costs for the employer that either keeps the miles or, decides to let their employees enjoy them.

This paper provides methodological tools and considers the reasons why it is difficult to address the controversial question, “Are fallacies frequent?” After preliminary remarks on the need to clarify the meaning of both ‘fallacy’ and ‘frequency,’ this paper shows that the emphasis on whether fallacies occur frequently is recent and bound to contemporary definitions that make it a necessary condition. Then, it discusses three different, debated empirical approaches that are intended to support the claim that fallacies are frequent. All of (...) them raise doubts or objections or are even controversial from a methodological point of view. Ultimately, more empirical research is needed to answer this question. (shrink)

An overwhelming majority of business travelers are now members of frequent flier programs operated by the airline industry. This article addresses relevant ethical issues, particularly employee perceptions of ethical issues, in such programs. A structured questionnaire technique, supported by personal interviews, was used to gather insights into frequent flier practices and attitudes. A fundamental conclusion of the research is that (1) significant ethical dilemmas are posed by frequent flier programs, (2) employees and employers generally choose to ignore these ethical dilemmas, (...) and (3) employee perception of the ethical issues in frequent flier programs is not significantly influenced by employee attributes such as education level, salary, organizational position, age or sex. Recommendations are offered to reduce the inherent ethical dilemmas in frequent flier programs. (shrink)

Cuckoldry is an adaptive problem faced by parentally investing males of socially monogamous species (e.g., humans and many avian species). Mate guarding and frequent in-pair copulation (IPC) may have evolved as anti-cuckoldry tactics in avian species and in humans. In some avian species, the tactics are used concurrently, with the result that mate guarding behaviors and IPC frequency are correlated positively. In other avian species, the tactics are compensatory, with the result that mate guarding behaviors and IPC frequency are correlated (...) negatively. The relationship between mate guarding and IPC frequency in humans is unknown. Avian males that use these tactics concurrently share with human males an inability to guard a female partner continuously during her peak fertile period. We hypothesized, therefore, that men’s mate guarding and IPC frequency function as concurrent anti-cuckoldry tactics, resulting in a positive correlation between them. Study 1 (n=305) secured men’s self-reports of mate guarding and IPC frequency. Study 2 (n+367) secured women’s reports of their partners’ mate guarding and IPC frequency. The concurrent tactics hypothesis was supported in both studies: Men’s mate guarding and IPC frequency are correlated positively, and this association is not attributable to male age, female age, relationship satisfaction, relationship length, or time that the couple spends together. The Discussion section addresses potential limitations of this research and future research directions. (shrink)

This paper, in the form of a frequently asked questions page (FAQ), addresses outstanding questions about “shadow enhancers”, quasi‐redundant cis‐regulatory elements, and their proposed roles in transcriptional control. Questions include: What exactly are shadow enhancers? How many genes have shadow/redundant/distributed enhancers? How redundant are these elements? What is the function of distributed enhancers? How modular are enhancers? Is it useful to study a single enhancer in isolation? In addition, a revised definition of “shadow enhancers” is proposed, and possible mechanisms of (...) shadow enhancer function and evolution are discussed. (shrink)

In this article, we present a new approach for frequent pattern mining that runs fast for both sparse and dense databases. Two algorithms, FEM and DFEM, based on our approach are also introduced. FEM applies a fixed threshold as the condition for switching between the two mining strategies; meanwhile, DFEM adopts this threshold dynamically at runtime to best fit the characteristics of the database during the mining process, especially when minimum support threshold is low. Additionally, we present optimization techniques for (...) the proposed algorithms to speed the mining process, reduce the memory usage, and optimize the I/o cost. We also analyze in depth the performance of FEM and DFEM and compare them with several existing algorithms. The experimental results show that FEM and DFEM achieve a significant improvement in execution time and consume less memory than many popular FPM algorithms including the well-known Apriori, FP-growth, and Eclat. (shrink)

Protein redox reactions are one of the most basic and important biochemical actions. As amino acids are weak redox mediators, most protein redox functions are undertaken by protein cofactors, which include organic ligands and transition metal ions. Since both kinds of redox cofactors were available in the pre‐protein RNA world, it is challenging to explore which one was more involved in redox processes of primitive proteins? In this paper, using an examination of the redox cofactor usage of putative ancient proteins, (...) we infer that organic ligands participated more frequently than transition metals in redox reactions of primitive proteins, at least as protein cofactors. This is further supported by the relative abundance of amino acids in the primordial world. Supplementary material for this article can be found on the BioEssays website. BioEssays 30:766–771, 2008. © 2008 Wiley Periodicals, Inc. (shrink)

The aim of the paper is to identify and categorize frequent patterns describing interactions between users in social networks. We analyze a social network with relationships between users that evolve in time already identified. In our research, we discover patterns based on frequent interactions between groups of users. The patterns are described by the characteristics of these interactions, such as their reciprocity, or the relative difference between estimations of global influences of the users participating in the discussions. The modification of (...) the apriori algorithms is applied as one of the methods for pattern identification. The analyzed social network is built using the data set containing data from the Polish blog website salon24, which concerns mostly socio-political issues. (shrink)

The complex health and social circumstances of living-at-risk, frequent users of emergency departments (aREDFUs) in the health jurisdictions of high-income countries, and the related, significant challenges posed for emergency departments and the health care providers working within them, are identified and explored in the paper. Ethical analyses of a set of relevant domains are performed, i.e., individual and relational autonomy considerations, relevant social construction and personal responsibility conceptions, patient welfare principles (beneficence, nonmaleficence, continuity of care), harm reduction methodologies and their (...) applications, health equity, and justice considerations of the distributive, formal and social types. The outcomes of these analyses demonstrate that there are ethically compelling reasons for emergency departments to adopt an ethics-informed, policy-based approach to the longitudinal care and management of living-at-risk, frequent users of emergency departments. From a formal justice perspective, the development and uses of such an approach are justified by a demonstrable relevant difference between living-at-risk, frequent users of emergency departments and other persons and groups of patients who visit emergency departments. We propose an example of such a policy-based approach. Examples of possible, pragmatic applications of this approach, which help ensure that aREDFUs who present to the ED are managed in a fair and optimally consistent manner, are provided for the consideration of an urban emergency department’s policymaking working group. (shrink)

Chapter 6 explores a case in which opportunities to rescue nearby strangers arise very frequently. In this case, it seems one is not required to take every individual opportunity to help, even if one is required to take some. The chapter develops a view of requiring reasons and permitting reasons that explains this claim. According to this view, “lifetime” features can amplify (cost-based and autonomy-based) permitting reasons not to save strangers. The chapter then asks whether it can be permissible not (...) to respond to a frequently occurring opportunity to help even when it would be wrong not to respond to an otherwise similar rarely occurring opportunity to help. It argues that, while frequency cannot itself make this kind of moral difference, considerations of cost and autonomy correlated with frequency can. Such considerations can make it permissible to rescue one near stranger rather than two distant strangers. (shrink)

The goal of this paper is to correct a widespread misconception about the work of Robert Leslie Ellis and John Venn, namely that it can be considered as the ‘British empiricist’ reaction against the traditional theory of probability. It is argued, instead, that there was no unified ‘British school’ of frequentism during the nineteenth century. Where Ellis arrived at frequentism from a metaphysical idealist transformation of probability theory’s mathematical calculations, Venn did so on the basis of an empiricist (...) critique of its ‘inverse application’. (shrink)

Quite often the compatibility of the EPR correlations with the relativity theory has been questioned; it has been stated that “the first in time of two correlated measurements instantaneously collapses the other subsystem”; it has been suggested that a causal asymmetry is built into the Feynman propagator. However, the EPR transition amplitude, as derived from the S matrix, is Lorentz andCPT invariant; the correlation formula is symmetric in the two measurements irrespective of their time ordering, so that the link of (...) the correlations is the Feynman zigzag, and that causality isCPT invariant at the microlevel; finally, although the Feynman propagator has theP andCT symmetries, no causal asymmetry follows from that. As for Stapp's views concerning “process” and “becoming,” and his Whiteheadean concept of an advancing front, I object that they belong to “factlike macrophysics,” and are refuted at the microlevel by the EPR phenomenology, which displays direct Fokker-like space-time connections. The reason for this is a radical one. The very blending of a space-time picture and of a probability calculus is a paradox. The only adequate paradigm is one denying objectivity to space-time—but this, of course, is also required by the complementary of the x and the k pictures, which only “look” compatible at the macrolevel. Therefore, the classical “objectivity” must yield in favor of “intersubjectivity.” Only the macroscopic preparing and measuring devices have “factlike” objectivity; the “transition” of the “quantal system” takes place beyond both thex and thek 4-spaces. Then, the intrinsic symmetries between retarded and advanced waves, and statistical prediction and retrodiction, entails that the future has no less (but no more) existence than the past. It is the future that is significant in “creative process,” the “elementary” forms of which should be termed “precognition” or “psychokinesis”—respectively symmetric to the factlike taboos that “we can neither know into the future nor act into the past.” It is gratifying that Robert Jahn, at the Engineering School of Princeton University, is conducting (after others) conclusive experiments demonstrating “low level psychokinesis”—a phenomenon implied by the very symmetry of the negentropy-information transition. So, what pierces the veil of “maya” is the (rare) occurrence of “paranormal phenomena.” The essential severance between “act” and “potentia” is not a spacelike advancing front, but the “out of” and the “into” factlike space-time. Finally, I do not feel that an adequate understanding of the EPR phenomenology requires going beyond the present status of relativistic quantum mechanics. Rather, I believe that the potentialities of this formalism have not yet been fully exploited. (shrink)