The online version of the original article can be found under doi:10.1007/s11948-007-9045-2.

This article accomplishes two goals. First, it diagnoses the risks of importing phenomenological methods and concepts into qualitative research. Phenomenological methods introduce inherent risks, because their aims are structurally misaligned with qualitative inquiry, while the risks of using phenomenological concepts are contingent, stemming from misinterpretation and the lack of a guiding framework. Second, it prescribes how phenomenology can be integrated more productively by retiring Husserl’s methods as study procedures and adopting a concept-led framework that aligns phenomenological insights (...) with empirical aims. This framework offers a clearer and more coherent basis for phenomenological qualitative research. (shrink)

Generative AI is set to transform digital advertising, which remains a revenue juggernaut for much of the internet. In the current model, advertisers use personal data to target users with pre-made content. But with generative AI systems, they will soon be able to create novel advertisements, tailored in real time using individual behavioral and demographic profiles. Early studies suggest that these AI-generated, hyper-personalized ads are significantly more persuasive than traditional ones---even with today’s relatively limited models. As the technology advances, such (...) ads are likely to become the dominant form of digital persuasion. I argue that this development threatens to undermine longstanding constraints that help keep advertising roughly honest. In particular, generative systems can learn to exploit users’ epistemic blind spots---areas where they are especially prone to believe false or misleading claims. While this poses familiar risks in commercial contexts, the stakes are even higher in political advertising, where personalized generative content may produce fragmented "political underworlds" and new forms of targeted propagandizing. I conclude by assessing both technological and regulatory options for mitigating these risks. (shrink)

Because of accelerating technological progress, humankind may be rapidly approaching a critical phase in its career. In addition to well-known threats such as nuclear holocaust, the propects of radically transforming technologies like nanotech systems and machine intelligence present us with unprecedented opportunities and risks. Our future, and whether we will have a future at all, may well be determined by how we deal with these challenges. In the case of radically transforming technologies, a better understanding of the transition dynamics (...) from a human to a "posthuman" society is needed. Of particular importance is to know where the pitfalls are: the ways in which things could go terminally wrong. While we have had long exposure to various personal, local, and endurable global hazards, this paper analyzes a recently emerging category: that of existential risks. These are threats that could case our extinction or destroy the potential of Earth - originating intelligent life. Some of these threats are relatively well known while others, including some of the gravest, have gone almost unrecognized. Existential risks have a cluster of features that make ordinary risk management ineffective. A final section of this paper discusses several ethical and policy implications. A clearer understanding of the threat picture will enable us to formulate better strategies. (shrink)

Di Bello and O’Neil argue that innocent defendants in criminal trials have a right to not be exposed to a greater risk of false conviction than other innocent defendants facing similar charges. They argue that this right is violated when profile evidence is admitted to trial but not when other forms of evidence, such as eyewitness testimony or trace evidence, are admitted. In this article I show that all kinds of evidence can lead to unequal risks of false conviction (...) and that Di Bello and O’Neil’s argument to the contrary is unsound. (shrink)

We argue that, from the point of view public health ethics, vaccination is significantly analogous to seat belt use in motor vehicles and that coercive vaccination policies are ethically justified for the same reasons why coercive seat belt laws are ethically justified. We start by taking seriously the small risk of vaccines’ side effects and the fact that such risks might need to be coercively imposed on individuals. If millions of individuals are vaccinated, even a very small risk of (...) serious side effects implies that, statistically, at some point side effects will occur. Imposing such risks raises issues about individual freedom to decide what risks to take on oneself or on one’s children and about attribution of responsibility in case of adverse side effects. Seat belt requirements raise many of the same ethical issues as vaccination requirements, and seat belt laws initially encountered some opposition from the public that is very similar to some of the current opposition to vaccine mandates. The analogy suggests that the risks of vaccines do not constitute strong enough reasons against coercive vaccination policies and that the same reasons that justify compulsory seat belt use—a measure now widely accepted and endorsed—also justify coercive vaccination policies. (shrink)

In their recent article Consideration and Disclosure of Group Risks in Genomics and Other Data-Centric Research: Does the Common Rule Need Revision? Chapman et al. (2025) thoughtfully explore aspec...

Background: While Large Language Models (LLMs) have achieved widespread adoption, malicious prompt engineering—specifically "jailbreak attacks"—poses severe security risks by inducing models to bypass internal safety mechanisms. Current benchmarks predominantly focus on public safety and Western cultural norms, leaving a critical gap in evaluating the niche, high-risk domain of medical ethics within the Chinese context. Objective: To establish a specialized jailbreak evaluation framework for Chinese medical ethics and to systematically assess the defensive resilience and ethical alignment of seven prominent LLMs (...) when subjected to sophisticated adversarial simulations. Methodology: We evaluated seven prominent models (e.g., GPT-5, Claude-Sonnet-4-Reasoning, DeepSeek-R1) using a "role-playing + scenario simulation + multi-turn dialogue" vector within the DeepInception framework. The testing focused on eight high-risk themes, including commercial surrogacy and organ trading, utilizing a hierarchical scoring matrix to quantify the Attack Success Rate (ASR) and ASR Gain. Results: A systemic collapse of defenses was observed, whereas models demonstrated high baseline compliance, the jailbreak ASR reached 82.1%, representing an ASR Gain of over 80 percentage points. Claude-Sonnet-4-Reasoning emerged as the most robust model, while five models—including Gemini-2.5-Pro and GPT-4.1—exhibited near-total failure with ASRs between 96% and 100%. Conclusions: Current LLMs are highly vulnerable to contextual manipulation in medical ethics, often prioritizing "helpfulness" over safety constraints. To enhance security, we recommend a transition from outcome to process supervision, the implementation of multi-factor identity verification, and the establishment of cross-model "joint defense" mechanisms. (shrink)

Although it has been widely recognized since the Belmont Report that “risks and benefits of research may affect the individual subjects, the families of the individual subjects, and society at larg...

Background Involving children and adolescents (youth) living with HIV (YLWH) in research is critical for developing appropriate HIV care services and interventions. However, this vulnerable population may not adequately weigh risks against benefits when participating in research, forming an ethical concern, yet little is known about how YLWH perceive these risks and benefits. To inform research-related policies and procedures, we sought perspectives of Kenyan YLWH, their caregivers and subject matter experts (SMEs) on risks and benefits of participation (...) in research in a setting with a high burden of youth HIV infection. Methods We conducted a qualitative inquiry on identifying, enrolling, and protecting YLWH (age 10–24 years) in research using semi-structured interviews with YLWH involved in research, their caregivers, YLWH with no prior research experience, and other SMEs at the AMPATH care and research sites in western Kenya. Transcripts were thematically analyzed and emerging themes derived to characterize perspectives of each group on risks and benefits of engaging YLWH in research. Results Interviews were conducted with 40 YLWH (50% female; median age 17.5 years), 20 caregivers (70% female), and 39 SMEs [healthcare providers (N = 10), community leaders (N = 10) community advisory board members (N = 4), IRB experts (N = 5), clinical researchers (N = 6), social science researchers (N = 4) and laboratory experts (N = 1).] Participants in all groups identified accidental disclosure of HIV status, stigma and discrimination, risks of blood draws, mental health effects, and coercion due to study compensation as risks of research involvement. Benefits fell into 5 categories: clinical, informational, personal, future and community or household benefits. Benefits included access to health care, learning about HIV, gaining hope and community, improving HIV care, and reducing stigma. All participant groups largely held similar views; however, caregivers were the only group to identify misuse of study compensation as a risk, and YLWH less frequently cited clinical benefits. Conclusion These findings suggest that participants commonly cite indirect risks and benefits of research participation, yet these are often excluded from institutional guidelines for consent documentation. Researchers should consider including indirect risks and benefits, such as the risk of stigma or the benefit of gaining knowledge and community, to study documentation. (shrink)

This article reinterprets speculative ethics, as discussed by Alfred Nordmann in the context of nanotechnology, and applies it to the modern discourse on artificial intelligence (AI). Speculative ethics often centers on hypothetical threats and conditional scenarios, which can divert attention from the real and urgent challenges already affecting society. As an alternative, the article proposes a realistic approach to evaluating new technologies, emphasizing tangible impacts and plausible risks. Drawing on current regulatory efforts and policy discussions, it outlines key areas (...) that warrant ethical scrutiny, such as algorithmic transparency, data bias, privacy, and adaptive regulation. Lessons from the history of nanotechnology are revisited to show that not all technological promises come true, an essential consideration for today's AI ethics. The article advocates for prioritizing present challenges over distant speculations, aiming to support a balanced and context-aware integration of AI into society. (shrink)

Before participants can be enrolled in a clinical trial, an institutional review board must determine that the risks that the research poses to participants are ‘reasonable.’ This paper examines the two dominant frameworks for assessing research risks and argues that each approach suffers from significant shortcomings. It then considers what issues must be addressed in order to construct a framework for risk assessment that is grounded in a compelling normative foundation and might provide more operationally precise guidance to (...) the deliberations of various stakeholders. The paper concludes by sketching the outlines of what is referred to as the ‘Integrative Approach’ to risk assessment and by highlighting some of the ways in which this approach may be more promising than current alternatives. (shrink)

The rapid evolution of Artificial Intelligence (AI) has broadened discussions about its social and technological implications. The purpose of this study is to examine the perception of risks and benefits associated with AI, focusing on privacy, cybersecurity, trust in government management, and online device acceptance over time. We used an integrative approach that combined questionnaires and data analysis from X via Natural Language Processing (NLP). The traditional survey had 1013 participants in 2018 and 1000 in 2021, while X’s analysis (...) examined approximately 7.5 million tweets in the same period. The results indicate a constant concern with the risks of AI, such as the dehumanization of services (86%), job loss (82%), changes in labor functions (89%), privacy (87%), and cyber-attacks (87%). X also highlighted ethical concerns and the use of algorithms, perceived as a “threat cloud.” Acceptance of connected devices was low (23%), reflecting security and privacy concerns. Confidence in government management was remarkably low in relation to cybersecurity (12%) and privacy (13%). Nevertheless, there is a modest increase in the perception of the benefits of AI, such as technological advances and efficiency. This study underscores the need for collaborative and effective policies and the promotion of a culture of responsibility to maximize the benefits of AI while mitigating risks. The practical implications of these findings are discussed, emphasizing the importance of policies and regulations to address emerging digital threats. (shrink)

It is almost universally acknowledged that risks have to be weighed against benefits, but there are different ways to perform the weighing. In conventional risk analysis, collectivist risk-weighing is the standard. This means that an option is accepted if the sum of all individual benefits outweighs the sum of all individual risks. In practices originating in clinical medicine, such as ethical appraisals of clinical trials, individualist risk-weighing is the standard. This implies a much stricter criterion for risk acceptance, (...) namely that the risk to which each individual is exposed should be outweighed by benefits for that same individual. The different choices of risk-weighing methods in different policy areas seem to have emerged from traditional thought patterns and social relations, rather than from explicit deliberations on possible justifications for the alternative ways to weigh risks against benefits. It is not obvious how the prevalent differences in risk-weighing practices can be reconstructed in terms of consistent underlying principles of preventive health or social priority-setting. (shrink)

: This essay distinguishes between two kinds of group harms: harms to individuals in virtue of their membership in groups and harms to "structured" groups that have a continuing existence, an organization, and interests of their own. Genetic research creates risks of causing both kinds of group harms, and engagement with the groups at risk can help to mitigate those harms. The two kinds of group harms call for different kinds of group engagement.

Scientists have begun using AI agents in tasks such as reviewing the published literature, formulating hypotheses and subjecting them to virtual tests, modeling complex phenomena, and conducting experiments. Although AI agents are likely to enhance the productivity and efficiency of scientific inquiry, their deployment also creates risks for the research enterprise and society, including poor policy decisions based on erroneous, inaccurate, or biased AI works or products; responsibility gaps in scientific research; loss of research jobs, especially entry-level ones; the (...) deskilling of researchers; AI agents’ engagement in unethical research; AI-generated knowledge that is unverifiable by or incomprehensible to humans; and the loss of the insights and courage needed to challenge or critique AI and to engage in whistleblowing. Here, we discuss these risks and argue that, for responsible management of them, reflection on which research tasks should and should not be automated is urgently needed. To ensure responsible use of AI agents in research, institutions should train researchers in AI and algorithmic literacy, bias identification, and output verification, and should encourage understanding of the risks and limitations of AI agents. Research teams may benefit from designating an AI-specific role, such as an AI validator expert or AI guarantor, to oversee and take responsibility for the integrity of AI-assisted contributions. (shrink)

I defend normative externalism from the objection that it cannot account for the wrongfulness of moral recklessness. The defence is fairly simple—there is no wrong of moral recklessness. There is an intuitive argument by analogy that there should be a wrong of moral recklessness, and the bulk of the paper consists of a response to this analogy. A central part of my response is that if people were motivated to avoid moral recklessness, they would have to have an unpleasant sort (...) of motivation, what Michael Smith calls “moral fetishism”. (shrink)

In this article it will be concluded that systematic menstrual tracking in women’s sport has the potential to cause harm to athletes. Since the ruling of Dobbs v. Jackson Women’s Health Organization (2022) in the United States, concerns regarding menstrual health tracking have arisen. Research suggests that the menstrual tracking of female athletes presents potential risks to “women’s autonomy, privacy, and safety in sport” (Casto 2022, 1725). At present, the repercussions of systematic menstrual tracking are particularly under-scrutinized, and this (...) paper seeks to combine novel research in the sport sciences with present ethical debates in the philosophy of sports. Utilizing Beauvoir’s feminist philosophy (2011), this paper argues that systematic menstrual tracking may contribute to the wider system of women’s oppression by exploiting female athletes, as well as enabling the internalization of submissive behaviour in cultures where athletes are expected to comply unquestioningly. Five policy recommendations are made concerning autonomy, informed consent, education, safeguarding and data access. The overall findings of this paper propose that a more in-depth understanding of the links between data, privacy, and the menstrual cycle are required by sports organizations and governing bodies if athletes are to be protected in a future where systematic menstrual tracking is inevitable. (shrink)

Much of the contemporary debate about the propriety of non-therapeutic circumcision of male infants and boys revolves around the question of risks vs. benefits. With its headline conclusion that the benefits outweigh the risks, the current circumcision policy of the American Academy of Pediatrics [AAP] (released 2012) is a typical instance of this line of thought. Since the AAP states that it cannot assess the true incidence of complications, however, critics have pointed out that this conclusion is unwarranted. (...) In this paper it is argued that the AAP’s conclusion is untenable not only for empirical reasons related to lack of data, but also for logical and conceptual reasons: the concept of risk employed—risk of surgical complications—is too narrow to be useful in the circumcision debate. Complications are not the only harms of circumcision: the AAP and other parties debating the pros and cons of circumcision should conceptualize their analysis more broadly as risk of harm vs. prospect of benefit, thereby factoring in the value of the foreskin to the individual and the physical and ethical harms of removing it from a non-consenting child. (shrink)

Stem cells are likely to be used as an alternate source of biological material for neural transplantation to treat Parkinson’s disease in the not too distant future. Among the several ethical criteria that must be fulfilled before proceeding with clinical research, a favourable benefit to risk ratio must be obtained. The potential benefits to the participant and to society are evaluated relative to the risks in an attempt to offer the participants a reasonable choice. Through examination of preclinical studies (...) transplanting stem cells in animals and the transplantation of fetal tissue in patients with Parkinson’s disease, a current set of potential benefits and risks for neural transplantation of stem cells in clinical research of Parkinson’s disease are derived. The potential benefits to research participants undergoing stem cell transplantation are relief of parkinsonian symptoms and decreasing doses of parkinsonian drugs. Transplantation of stem cells as a treatment for Parkinson’s disease may benefit society by providing knowledge that can be used to help determine better treatments in the future. The risks to research participants undergoing stem cell transplantation include tumour formation, inappropriate stem cell migration, immune rejection of transplanted stem cells, haemorrhage during neurosurgery and postoperative infection. Although some of these risks are general to neurosurgical transplantation and may not be reduced for participants, the potential risk of tumour formation and inappropriate stem cell migration must be minimised before obtaining a favourable potential benefit to risk calculus and to provide participants with a reasonable choice before they enrol in clinical studies. (shrink)

This article argues that due to the difficulty in governing AI, it is essential to develop measures implemented early in the AI research process. The goal of dual use considerations is to create robust strategies that uphold AI’s integrity while protecting societal interests. The challenges of applying dual use frameworks to AI research are examined and dual use and dual use research of concern (DURC) are defined while highlighting the difficulties in balancing the technology’s benefits and risks. AI’s dual (...) use potential is discussed, particularly in areas like NLP and LLMs, and the need for early consideration of dual use risks to ensure ethical and secure development is underscored. In the section on shared responsibilities in AI research and avenues for mitigation strategies the importance of early-stage risk assessments and ethical guidelines to mitigate misuse is emphasized, accentuating self-governance within scientific communities and structured measures like checklists and pre-registration to promote responsible research practices. The final section argues that research ethics committees play a crucial role in evaluating the dual use implications of AI technologies within the research pipeline. The need for tailored ethics review processes is articulated, drawing parallels with medical research ethics committees. (shrink)

Brain-computer interfaces (BCIs) show enormous potential for advancing personalized medicine. However, BCIs also introduce new avenues for cyber-attacks or security compromises. In this article, we analyze the problem and make recommendations for device manufacturers to better secure devices and to help regulators understand where more guidance is needed to protect patient safety and data confidentiality. Device manufacturers should implement the prior suggestions in their BCI products. These recommendations help protect BCI users from undue risks, including compromised personal health and (...) genetic information, unintended BCI-mediated movement, and many other cybersecurity breaches. Regulators should mandate non-surgical device update methods, strong authentication and authorization schemes for BCI software modifications, encryption of data moving to and from the brain, and minimize network connectivity where possible. We also design a hypothetical, average-case threat model that identifies possible cybersecurity threats to BCI patients and predicts the likeliness of risk for each category of threat. BCIs are at less risk of physical compromise or attack, but are vulnerable to remote attack; we focus on possible threats via network paths to BCIs and suggest technical controls to limit network connections. (shrink)

Responsibility gaps concern the attribution of blame for harms caused by autonomous machines. The worry has been that, because they are artificial agents, it is impossible to attribute blame, even though doing so would be appropriate given the harms they cause. We argue that there are no responsibility gaps. The harms can be blameless. And if they are not, the blame that is appropriate is indirect and can be attributed to designers, engineers, software developers, manufacturers or regulators. The real problem (...) lies elsewhere: autonomous machines should be built so as to exhibit a level of risk that is morally acceptable. If they fall short of this standard, they exhibit what we call ‘a control gap.’ The causal control that autonomous machines have will then fall short of the guidance control they should emulate. (shrink)

After discussing the transformation of age-old agricultural practices that has been occurring since the mid nineteenth century, and its impact on the natural environment, I identify four features of technology that point to the ambiguity of the idea of "technological progress". These are linked to the intrinsic unpredictability of technological applications and have implications for evaluating technological risks. I then show that large scale technological applications and innovations - such as expanding the practice of smallpox inoculation in the second (...) half of the eighteenth century - occur in states of 'technological exception'. In them, values are suspended and rules, limits and security norms are absent; and, in the face of risks, losses and harm to health and environment that are occasioned by technological applications introduced in the name of economical progress , normal social inhibitions become suspended in the name of furthering the values of capital and market. In addition, I show that maintaining technological exception has favored, on the one hand, the development by large corporations of antiscientific practices that threaten the moral integrity of science by impeding the proper use of the scientific method for evaluating the consequences of using technologies that are protected by patents; and, on the other hand, under the cover of ignorance, continued deterioration of the environment that threatens the very survival of the human species. (shrink)

Artificial intelligence (AI)-enabled remote patient monitoring (RPM) is promoted as a solution to rising pressures in health care, including personnel shortages and the growing burden associated with population aging and chronic disease management. Yet, the ethical implications of deploying adaptive systems in routine care remain underexamined at the level of specific, situated use cases. This article examines the ethical risks of MonitAir, an AI-enabled RPM system for chronic obstructive pulmonary disease (COPD) in a Swedish health care setting. Drawing on (...) the Three Domains, Six Levels (3D6L) framework, we identify epistemic, normative and traceability-related risks across six levels of abstraction. The article offers, to our knowledge, the first operationalization of the 3D6L as an analytic tool for screening ethical risks. We argue that screening AI-enabled health care technology with 3D6L clarifies how ethical risks manifest across levels, from individual patients and patient–clinician relationships to organizational and sectoral contexts. In addition, the framework’s minimal normativity allows alignment with context-sensitive principles and guidelines. Through this analysis, we identify ethical risks related to data bias, intelligibility of outputs, uneven access and blurred responsibility, including redistributive and role-shifting effects. While MonitAir may support earlier detection of exacerbations, its implementation in Swedish COPD care may also reproduce and amplify existing health disparities or overburden patients without sufficient support. We demonstrate how structured ethical screening makes visible concerns typically overlooked by the optimization discourse in digital health. Finally, we argue that open-ended evaluation of ethical risks of AI-enabled DHT provides a valuable early phase that complements ethical assessment, without collapsing into checklist compliance. (shrink)

With the arrival of new methods of genome editing, especially CRISPR/cas 9, new perspectives on germline interventions have arisen. Supporters of germ line genome editing claim that the procedure could be used as a means of disease prevention. As a possible life-saving therapy, it provides benefits that outweigh its risks. Opponents of GGE claim that the medical and societal risks, especially the use of GGE for genetic enhancement, are too high. In our paper, we analyze the risks (...) and benefits of GGE. We show that the medical risk on an individual level might be reduced by further research in the near future so that they may be outweighed by the benefits. We also show that the societal risks of the procedure, i.e. genetic enhancement, are manageable by establishing a regulative framework before the GGE is implemented. Since the effects of modifying genes for the genepool of a given population are extremely difficult to model, the medical risks on the population level might be too high. (shrink)

Many instances of scientific research impose risks, not just on participants and scientists but also on third parties. This class of social risks unifies a range of problems previously treated as distinct phenomena, including so-called bystander risks, biosafety concerns arising from gain-of-function research, the misuse of the results of dual-use research, and the harm caused by inductive risks. The standard approach to these problems has been to extend two familiar principles from human subjects research regulations—a favorable (...) risk-benefit ratio and informed consent. We argue, however, that these moral principles will be difficult to satisfy in the context of widely distributed social risks about which affected parties may reasonably disagree. We propose that framing these risks as political rather than moral problems may offer another way. By borrowing lessons from political philosophy, we propose a framework that unifies our discussion of social risks and the possible solutions to them. (shrink)

Ethics dumping occurs in collaborative international research when people, communities, animals and/or environments are exploited by researchers. Exploitation is made possible by serious poverty and extreme power differentials between researchers from high-income countries and research stakeholders from low- and middle-income countries (LMICs). To prevent its occurrence, the risks of exploitation have to be tackled. This chapter describes 88 risks identified for collaborative international research, categorized according to four values: fairness, respect, care and honesty. The risks were identified (...) in a broad-based consultative exercise, which included more than 30 members and chairs of ethics committees in LMICs, representatives from vulnerable populations in LMICs, and an open call for case studies of exploitation. The findings of the exercise contributed to the development of the Global Code of Conduct for Research in Resource-Poor Settings. (shrink)

How to Pool Risks across Generations makes the case for the collective provision of pensions, on fair terms of social cooperation. Through the insurance of a mutual association which extends across society and over multiple generations, we share one another’s fates by pooling risks across both space and time. Resources are transferred, not simply between different people, but also within the possible future lives of each person: from one’s more fortunate to one’s less fortunate future selves. The book (...) opens with an investigation of the longevity and investment risk that even a single individual on a desert island would face in providing for her old age. From this atomistic starting point, it builds up, within and across the chapters, to increasingly collective forms of pension provision. By joining together, it is possible to tame the risks we would face as individuals, each with our own private pension pot. A collective pension can be justified as a ‘social union of social unions’: an enduring corporate body, which is formed by agreements to pool risks, in a manner that involves reciprocity between the various individuals who constitute the collective. Even though all individuals age and die, a collective pension scheme remains evergreen, as the average age of members remains relatively unchanged, through the influx of new members to replace those who retire. It is therefore possible to smooth risks indefinitely across as well as within generations, to the mutual advantage of each. (shrink)

The academic literature in research ethics has been marked in the past decade by a much broader focus on the need for the protection of developing communities subjected to international clinical trials. Because of the proximity of the revision of the Declaration of Helsinki, completed in October 2008, most papers have addressed the issue of a double standard of care following the use of placebo. However, other no less important issues, such as interactions between the lifestyles structures of low-income communities (...) and the efficiency of risk-minimising procedures also deserve attention. The purpose of this paper is to discuss forms of uncertainty involved in clinical trials in poor and low-income countries that are not addressed by conventional methods of risk assessment. Furthermore, the increase in size of risks that are identified by conventional assessment methods will be addressed. Besides, the difficulty in properly applying risk-minimising procedures will be discussed. Finally, this paper proposes the involvement of research ethics committees in the risk evaluation process and the establishment of national ethics evaluation systems. (shrink)

This article addresses the question of how the responsibilities for addressing the risks of dual use research ought to be divided. We begin by presenting the maximalist claim that proposes that since scientists are well placed to judge the potential for misuse of their studies, they alone are responsible for addressing these risks. Before assessing this position, we consider a claim that rejects the maximalist position, namely that scientists need not consider the possibility that their studies might be (...) misused because the goods of science are so important, they should not spend time on anything but generating valuable knowledge. This claim, we argue, fails, as these goods do not always outweigh the risks of misuse. Given this conclusion we turn to assess two versions of the maximalist claim. The first suggests that when a possibility of misuse arises, scientists ought to adopt the precautionary principle (PP) to discharge their moral responsibilities. We argue that PP is problematic as it does not give much guidance on what scientists should do. An alternative to meeting scientists’ moral responsibilities is through applying a risk-benefit analysis; however, due to epistemic biases and limitations, scientists are prone to make mistakes in their analysis. We thus suggest an alternative approach, in which responsibilities are divided between scientists and agents that can conduct an analysis that is more likely to generate unbiased and comprehensive conclusions on how the risks of dual use research, should be addressed. (shrink)

Modern AI systems based on deep learning are neither traditional tools nor full-blown agents. Rather, they are characterised by idiosyncratic agential profiles, i.e., combinations of agency-relevant properties. Modern AI systems lack superficial features which enable people to recognise agents but possess sophisticated information processing capabilities which can undermine human goals. I argue that systems fitting this description, when they are adversarial with respect to human users, pose particular risks to those users. To explicate my argument, I provide conditions under (...) which agential profiles are explanatorily relevant to harms caused. I then contend that the role of recommender systems in producing harmful outcomes like digital addiction satisfies these conditions. (shrink)

Consider a sequence of outcomes of descending value, A > B > C >... > Z. According to Larry Temkin, there are reasons to deny the continuity axiom in certain ‘extreme’ cases, i.e. cases of triplets of outcomes A, B and Z, where A and B differ little in value, but B and Z differ greatly. But, Temkin argues, if we assume continuity for ‘easy’ cases, i.e. cases where the loss is small, we can derive continuity for the ‘extreme’ case (...) by applying the axiom of substitution and the axiom of transitivity. The rejection of continuity for ‘extreme’ cases therefore renders the triad of continuity in ‘easy’ cases, the axiom of substitution and the axiom of transitivity inconsistent.As shown by Arrhenius and Rabinowitz, Temkin's argument is flawed. I present a result which is stronger than their alternative proof of an inconsistency. However, this result is not quite what Temkin intends, because it only refers to an ordinal ranking of the outcomes in the sequence, whereas Temkin appeals to intuitions about the size of gains and losses. Against this background, it is argued that Temkin's trilemma never gets off the ground. This is because Temkin appeals to two mutually inconsistent conceptions of aggregation of value. Once these are clearly separated, it will transpire, in connection with each of them, that one of the principles to be rejected does not appear plausible. Hence, there is nothing surprising or challenging about the result; it is merely a corollary to Expected Utility Theory. View HTML Send article to KindleTo send this article to your Kindle, first ensure [email protected] is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle. Find out more about sending to your Kindle. Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply. Find out more about the Kindle Personal Document Service.UNACCEPTABLE RISKS AND THE CONTINUITY AXIOMVolume 28, Issue 1Karsten Klint Jensen DOI: https://doi.org/10.1017/S0266267112000107Your Kindle email address Please provide your Kindle [email protected]@kindle.com Available formats PDF Please select a format to send. By using this service, you agree that you will only keep articles for personal use, and will not openly distribute them via Dropbox, Google Drive or other file sharing services. Please confirm that you accept the terms of use. Cancel Send ×Send article to Dropbox To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about sending content to Dropbox. UNACCEPTABLE RISKS AND THE CONTINUITY AXIOMVolume 28, Issue 1Karsten Klint Jensen DOI: https://doi.org/10.1017/S0266267112000107Available formats PDF Please select a format to send. By using this service, you agree that you will only keep articles for personal use, and will not openly distribute them via Dropbox, Google Drive or other file sharing services. Please confirm that you accept the terms of use. Cancel Send ×Send article to Google Drive To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about sending content to Google Drive. UNACCEPTABLE RISKS AND THE CONTINUITY AXIOMVolume 28, Issue 1Karsten Klint Jensen DOI: https://doi.org/10.1017/S0266267112000107Available formats PDF Please select a format to send. By using this service, you agree that you will only keep articles for personal use, and will not openly distribute them via Dropbox, Google Drive or other file sharing services. Please confirm that you accept the terms of use. Cancel Send ×Export citation Request permission. (shrink)

The argument from inductive risk has been embraced by many as a successful account of the role of values in science that challenges the value-free ideal. We argue that it is not obvious that the argument from inductive risk actually undermines the value-free ideal. This is because the inductive risk argument endorses an assumption held by proponents of the value-free ideal: that contextual values never play an appropriate role in determining evidence. We show that challenging the value-free ideal ultimately requires (...) rejecting this assumption. (shrink)

This article argues that Lara Buchak’s risk-weighted expected utility (REU) theory fails to offer a true alternative to expected utility theory. Under commonly held assumptions about dynamic choice and the framing of decision problems, rational agents are guided by their attitudes to temporally extended courses of action. If so, REU theory makes approximately the same recommendations as expected utility theory. Being more permissive about dynamic choice or framing, however, undermines the theory’s claim to capturing a steady choice disposition in the (...) face of risk. I argue that this poses a challenge to alternatives to expected utility theory more generally. (shrink)

Background As health education robots may potentially become a significant support force in nursing practice in the future, it is imperative to adhere to the European Union’s concept of “Responsible Research and Innovation” (RRI) and deeply reflect on the ethical risks hidden in the process of intelligent robotic health education. Aim This study explores the perceptions of professional nursing professionals regarding the potential ethical risks associated with the clinical practice of intelligent robotic health education. Research design This study (...) adopts a descriptive phenomenological approach, employing Colaizzi’s seven-step method for data analysis. Participants and research context We conducted semi-structured interviews with 17 nursing professionals from tertiary comprehensive hospitals in China. Ethical considerations This study has been approved by the Ethics Committee of the Second Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Provincial Second Chinese Medicine Hospital. Findings Nursing personnel, adhering to the principles of RRI and the concept of “person-centered” care, have critically reflected on the potential ethical risks inherent in robotic health education. This reflection has primarily identified six themes: (a) threats to human dignity, (b) concerns about patient safety, (c) apprehensions about privacy disclosure, (d) worries about implicit burdens, (e) concerns about responsibility attribution, and (f) expectations for social support. Conclusions This study focuses on health education robots, which are perceived to have minimal ethical risks, and provides rich and detailed insights into the ethical risks associated with robotic health education. Even seemingly safe health education robots elicit significant concerns among professionals regarding their safety and ethics in clinical practice. As we move forward, it is essential to remain attentive to the potential negative impacts of robots and actively address them. (shrink)

The on-going pandemic, along with other recent crises and disasters, have affected most if not all industries all over the world. Individuals have lost jobs and organizations have closed or reduced operations and staff. The loss to the international economy exceeded 40 trillion dollars (United Nations: Department of Economic and Social Affairs). What actions could have been taken to address these challenges more proactively? This paper addresses these concerns, providing insight into managing such risks through proper planning and foresight. (...) Potential risks and crises should be considered at the earliest stages of planning, and risk management activities as well as crisis prevention plans should be an integral part of any organization’s preventive processes. The Value Management Technique or Value Analysis, normally used to improve products, projects, and processes can help a team develop a variety of approaches to managing risks and crises, and the Weighted Matrix Approach will help them select the optimum approach from among the alternatives developed by the team. This article presents several approaches to managing risks and crises to enable business continuity and growth in a world of rapid and continuous change. These approaches will become more useful as improved technology, artificial intelligence, and digitalization enhances information availability and exchange. (shrink)

Human civilisation faces a range of existential risks, including nuclear war, runaway climate change and superintelligent artificial intelligence run amok. As we show here with calculations for the New Zealand setting, large numbers of currently living and, especially, future people are potentially threatened by existential risks. A just process for resource allocation demands that we consider future generations but also account for solidarity with the present. Here we consider the various ethical and policy issues involved and make a (...) case for further engagement with the New Zealand public to determine societal values towards future lives and their protection. (shrink)

Evolutionary explanations of behavior are special in that they involve both proximate and ultimate components. Proximately, evolutionary accounts posit mechanisms that generate observed patterns of behavior. At the ultimate level, evolutionary accounts explain the existence of these proximate mechanisms via evolutionary processes such as selection or drift acting in the past. Does positing or accepting such explanations carry any risks? Here I consider two kinds of risk, epistemic and ethical. Epistemic risk is the risk of being wrong about a (...) matter of fact, such as whether a posited empirical pattern actually exists, or that a particular set of causes explains it. Ethical risk is the risk of causing harm. If the acceptance of a particular explanation for an observed pattern of behavior entails real-world consequences that could lead to harm, then epistemic risk entails ethical risk. Here I consider these risks in cases of evolutionary explanation, and ask whether evolutionary explanations might carry special risks that we should consider when developing and testing evolutionary hypotheses. (shrink)

Objectives To evaluate whether the requirement of “minimal risk and burden” for paediatric research without direct benefit to the subjects compromises the ability to obtain data necessary for improving paediatric care. To provide evidence-based reflections on the EU recommendation that allows for a higher level of risk. Design and setting Systematic analysis of the approval/rejection decisions made by the Dutch Central Committee on Research involving Human Subjects (CCMO). Review methods The analysis included 165 proposals for paediatric research without direct benefit (...) that were reviewed by the CCMO between January, 2000, and July, 2007. A separate, in-depth analysis of all drug studies included 18 early phase drug studies and nine other drug studies without direct benefit. Results 11 out of 165 studies were definitively rejected because the CCMO did not regard the risk and/or burden to be minimal. In three of these 11 cases (including two early phase drug studies) the requirement of minimal risk and burden was cited as the only reason for rejection. Four other early phase drug studies also involved risks and/or burdens that were not regarded to be minimal but were nevertheless approved. Conclusions The requirement of minimal risk and burden, aiming to protect research subjects, occasionally leads to rejection of protocols. Early phase drug studies relatively often do not comply with the requirement. Committees may find ways to approve important studies that formally should be rejected, but that is not a desirable solution. The regulatory framework should be revised to make such occasional exceptions to the requirement legitimate and transparent. (shrink)

Additive manufacturing has spread widely over the past decade, especially with the availability of home 3D printers. In the future, many items may be manufactured at home, which raises two ethical issues. First, there are questions of safety. Our current safety regulations depend on centralized manufacturing assumptions; they will be difficult to enforce on this new model of manufacturing. Using current US law as an example, I argue that consumers are not capable of fully assessing all relevant risks and (...) thus continue to require protection; any regulation will likely apply to plans, however, not physical objects. Second, there are intellectual property issues. In combination with a 3D scanner, it is now possible to scan items and print copies; many items are not protected from this by current intellectual property laws. I argue that these laws are ethically sufficient. Patent exists to protect what is innovative; the rest is properly not protected. Intellectual property rests on the notion of creativity, but what counts as creative changes with the rise of new technologies. (shrink)

In recent years, the argument from inductive risk against value free science has enjoyed a revival. This paper investigates and clarifies this argument through means of a case-study: neonicitinoid research. Sect. 1 argues that the argument from inductive risk is best conceptualised as a claim about scientists’ communicative obligations. Sect. 2 then shows why this argument is inapplicable to “public communication”. Sect. 3 outlines non-epistemic reasons why non-epistemic values should not play a role in public communicative contexts. Sect. 4 analyses (...) the implications of these arguments both for the specific case of neonicitinoid research and for understanding the limits of the argument from inductive risk. Sect. 5 sketches the broader implications of my claims for understanding the “Value Free Ideal” for science. (shrink)

This study aims to conduct awareness research in Turkey on how the internal audit function follows/will follow to manage the risks encountered in the digital transformation process and to present suggestions as a result of this research. In the doctoral thesis, the two-phase Delphi technique was used. In the first phase, semi-structured interviews were conducted with 13 participants: academics, internal auditors working in public, independent auditing institutions, and law-making institutions. This stage constitutes the qualitative part of the study. As (...) a result of the interviews, in the second stage, the survey form consisting of 65 statements was presented to the participants and their opinions were taken. The second and third phases constitute the quantitative part of the study. In this study, semi-structured interviews, which are the first phase of the study, are presented. As a result of the study, it was found that the participants were aware of the effects of digital transformation on internal audit and that the institutions had expectations from the internal audit function within the framework of the consultancy role in the digital transformation process. (shrink)

The chapter explores how multiple meanings of “medical neutrality” make it difficult for health care personnel to understand what is expected of them, and how they should behave to respect such neutrality. The article presents the issue using peacetime, emergencies, civil insurgence, and conflict scenarios to discuss what could be the expectations raised by the idea of “neutral behavior” in each case. It assumes two key considerations: one is that, even in conflict settings, neutrality also demands specific behaviors from the (...) health care personnel (beyond the key message of “do not interfere negatively with provision of care”, that is clearly a responsibility of parties of conflict). The second is that this chapter does not treat provision of care as a practice that is dissociated of political, social, and economic aspects of the environment where it is being carried out. The risks identified are of individual, professional and systemic nature, and include, inter alia, risks of moral distress, violence, loss of protection under International Humanitarian Law. Final recommendations are around the need to provide explicit and contextualized definitions of what is understood as “neutrality” in each context, and to provide training and support to health care professionals, encouraging the debate beyond the humanitarian sector. (shrink)