Abstract

This chapter focuses on studies from animal and human-based research that reflect a general approach and provide converging evidence in support of the working-with-memory model. It suggests that as WWM structures, regions of the frontal cortex operate strategically on information delivered to the medial-temporal/diencephalic system and recovered from it, thereby conferring “intelligence” to what essentially is a “stupid” medial temporal lobe/diencephalic system. The FC is needed to implement encoding and retrieval strategies. The latter includes initiating and directing search in accordance with the demands of the task, monitoring and verifying recovered memories, and placing them in the proper temporal-spatial context.