Synthetic Biology Creates Living Computers

Most people have at least a fuzzy idea of what DNA is. Ask about RNA, though, and unless you are talking to a biologist, you are likely to get even more handwaving. We hackers might have to reread our biology text books, though, since researchers have built logic gates using RNA.

Sometimes we read these university press releases and realize that the result isn’t very practical. But in this case, the Arizona State University study shows how AND, OR, and NOT gates are possible and shows practical applications with four-input AND gates and six-input OR gates using living cells. The key is a construct known as an RNA toehold switch (see video below). Although this was worked out in 2012, this recent study shows how to apply it practically.

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Quick Robin! The Bat Keychain!

We don’t know if Batman has a keychain for the keys to the Bat mobile, the Bat copter, and all his other vehicles. But we are guessing if he did, it didn’t look like the one [krishnan793] picked up cheap. It had a little button that lit up some LEDs and played a little tune. [Krishnan] thought he could do better with an ESP8266. After chopping up some headphones and adding a LiPo battery, he wound up with an improved key chain you can see in the video below. The first video is the before video. The second is after the modification. Sure, it is only a small improvement on LEDs and a simple tune, but now it is hackable to do more interesting things if you want to take the trouble to do so.

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Silicone Molds For Stove-Top Metal Casting

Casting metal parts from 3D-printed plastic or Styrofoam models is all the rage these days, and for good reason — casting is a way to turn one-offs into mass-produced parts. Seems like most of the metal casting projects we feature are aluminum in sand molds, though, so it’s refreshing to see a casting project using silicone molds to cast low-melting point metals.

Don’t get us wrong — sand-cast aluminum is a great method that can even be used to build a lathe from scratch. But not everyone wants to build a foundry and learn the sometimes fussy craft of creating sand molds. [Chris Deprisco] wanted to explore low-melting point bismuth alloys and set about making silicone rubber molds of a 3D-printed Maltese falcon. The bismuth-tin alloy, sold as a substitute for casting lead fishing weights, melts on at 281°F (138°C) and is cool enough for the mold to handle. Initial problems with bubbles in the cast led to a pressure vessel fix, and a dull, grainy surface was fixed by warming the mold before the pour. And unlike sand molds, silicone molds are reusable.

Of course if aluminum is still your material of choice, there’s no need for a complicated foundry. A tuna can, a loaf of bread, and a handful of play sand is all you need to make custom parts.

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The Hackaday Prize: Exoskeletons For The Masses

While medical facilities continue to improve worldwide, access to expensive treatments still eludes a vast amount of people. Especially when it comes to prosthetics, a lot of people won’t be able to afford something so personalized even though the need for assistive devices is extremely high. With that in mind, [Guillermo Herrera-Arcos] started working on ALICE, a robotic exoskeleton that is low-cost, easy to build, and as an added bonus, 100% Open Source.

ALICE’s creators envision that the exoskeleton will have applications in rehabilitation, human augmentation, and even gaming. Also, since it’s Open Source, it could also be used as a platform for STEM students to learn from. Currently, the team is testing electronics in the legs of the exoskeleton, but they have already come a long way with their control system and getting a workable prototype in place. Moving into the future, the creators, as well as anyone else who develops something on this platform, will always be improving it and building upon it thanks to the nature of Open Source hardware.