You can accelerate diagnosis times
Ask your patient:
- Do you have more than one blister or lesion in your mouth?
- Have your blisters or lesions lasted for more than a week?
- Have you continually had blisters or lesions that don’t heal?
- Do you have blisters or lesions in any locations outside the mouth?
If your patient answers YES to three or more of these questions, a biopsy should be considered. Both conventional H&E histology (in formalin) and DIF (in Michel’s/Zeus) are needed for a diagnosis. Specimens must contain intact epithelium over the underlying connective tissue.